Chemists at IRB Barcelona patent and present a shuttle capable of transporting molecules into the brain; this achievement could facilitate the treatment of diseases with no therapy available.
This image shows the detail of one millimeter of a mouse brain. In green, capillaries that form part of the blood-brain barrier; in red, molecules attached to the shuttle patented by IRB Barcelona have managed to cross the barrier and reach the brain (black background).
Credit:Benjamí Oller, IRB Barcelona
The study has involved scientists from the Institute for Stroke and Dementia Research of Munich and the Institute of Nanoscience of Aragon.
Roger Prades, Benjamí Oller-Salvia, Susanne M. Schwarzmaier, Javier Selva, María Moros, Matilde Balbi, Valeria Grazffl, Jesus M. de La Fuente, Gustavo Egea, Nikolaus Plesnila, Meritxell Teixidó, and Ernest Giralt
Angewandte Chemie Intl Edition (February 2015) DOI: 10.1002/anie.201411408