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An Old Problem With DNA Solved

In a recent publication, researchers achieved new accuracy in the ability to measure energy differences between states of molecules, thus predicting which states will be observed.

It has been known since the seventies that excessive causes to reverse its twist, from a right-handed spiral to a left-handed one. in the Z form is treated by our natural repair enzymes as damaged, and is therefore usually deleted from the cell. Deletion of can lead to cancer or to other problems, so the B-Z transition is no mere curiosity. However such is the complexity of the molecule that a theoretical explanation which correctly predicts the amount of to do this has never before been found.

Dr. and of the University of Luxembourg have now been able to find a method of calculation which predicts this transition with unprecedented accuracy. With this success in describing the most enigmatic of molecules, the team is optimistic that they will be able to perform similar mathematical analyses for a variety of other substances. “It will enable us to predict material properties such as melting temperatures or elasticity. And this will be done with high accuracy using our new technique. Hence, we can now design new materials and biomaterials on the computer more effectively than before,” said Prof. .


Prof Schilling and Dr Berryman are physicists at the University’s Physics and Material Sciences Research Unit, which comprises a team of 50 researchers.

University of Luxembourg