An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine in a study published in the online early edition of the Proceedings of the National Academy of Sciences (PNAS).
Ovarian cancer cells are shown forming small tumor. An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia (CLL) may also prove effective against ovarian cancer.
Credit: Image courtesy of University of Gothenburg.
Co-authors include Suping Zhang, Bing Cui, Hsien Lai, Grace Liu, Emanuela M. Ghia, George Widhopf, Zhuhong Zhang, Christina C.N. Wu, Liguang Chen, Rongrong Wu, Richard Schwab and Dennis A. Carson, all at UC San Diego Moores Cancer Center.
Funding for this research came, in part, from the National Institutes of Health (grant PO1-CA081534), the California Institute for Regenerative Medicine, the Blood Cancer Research Fund, UCSD Foundation and Cancer Center Support Grant P30CA23100.