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Autism genes activate during fetal brain development

Scientists at the University of California, San Diego School of Medicine have found that mutations that cause autism in children are connected to a pathway that regulates . The research, led by , PhD, assistant professor in the Department of Psychiatry, is published in the journal Neuron.

Autism mutations may influence brain size through RhoA pathway during .


Co-authors include Xinping Yang, and Marc Vidal, Dana-Farber Cancer Institute; Irma Lemmens and Jan Tavernier, , Belgium; and Jonathan Sebat, Beyster Center for Genomics of Psychiatric Diseases and UCSD.

This research was funded, in part, by National Institutes of Health (grants R01MH091350, R01HD065288, R21MH104766 and R01MH105524).

University of California – San Diego