Research from Lund University in Sweden shows that the protein COMP, which mainly exists in cartilage, can also be found in breast cancer tumours in patients with a poor prognosis. Studies on mice also showed that COMP contributed to the development and metastasis of the breast cancer.
High expression of COMP in breast cancer cells, seen here in brown, is associated with poor clinical prognosis for the patient. Cancer cells expressing COMP become more invasive and change their metabolism, which allows them to survive better and spread to other organs.
Credit: Photo: Anna Bloms / Lund University