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Computer model of nerve cells provides insights into communication problems in diseases of the brain

Study shows the between the structure and function of neurons

[Nerve cells communicate with each]
Nerve cells communicate with each other via intricate projections. In brain diseases such as Alzheimer’s and Parkinson’s these extensions atrophy, thereby causing connectivity problems.
Credit: DZNE/


Original publication:

Dendritic Structural Degeneration is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease. Zuzana Šišková, , , Detlef Friedrichs, , , Julika Pitsch, Susanne Schoch, Albert Becker, Heinz von der Kammer, Stefan Remy. Neuron, 2014, doi: 10.1016/j.neuron.2014.10.024

DZNE – German Center for Neurodegenerative Diseases