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Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults. In a study published in the August 2012 print edition of Arteriosclerosis, Thrombosis, and Vascular Biology, an American Heart Association peer-reviewed medical journal, [...]

Arsenic is a natural element in the environment, sometimes found in air, soil and water. Arsenic contaminated water is a global threat, currently affecting more than 100 million people. Both genetic and epigenetic changes drive arsenic-induced carcinogenesis and lung cancer is one of the main consequences of this process. Researchers from the British Columbia Cancer [...]

In lung cancer, patients who benefit from drugs like erlotinib will inevitably develop drug resistance. This is heralded by cancer growth and increasing tumor-related symptoms. Now scientists are investigating a second line of defense by studying the use of the novel AKT inhibitor MK-2206 in combination with erlotinib for patients whose benefit from erlotinib has [...]

The dual HIV-TB epidemic has posed a challenge for both TB and HIV efforts at all levels. Although the number of people living with HIV (PLHIV) screened for TB increased almost 12-fold, (from nearly 200 000 to over 2.3 million people) and testing for HIV among TB patients increased 5-fold (from 470,000 to over 2.2 [...]

In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk. A University of Colorado Cancer Center study published in the journal Cancer Prevention Research details one novel mechanism of this risk: long-term oxygen depletion stimulates signals that promote tumor growth. In addition, this early study – performed [...]