3 days popular7 days popular1 month popular3 months popular

Diabetic hippocampal injury alleviated by sericin

Preliminary studies by Dr. and colleagues from have shown that sericin might improve aberrant Akt signaling, decrease heme oxygenase-1 expression in the hippocampus and cerebral cortex, and reduce the apoptosis of in , thus protecting the nervous system.

Recently, it is reported that the growth hormone/insulin-like growth factor 1 axis undergoes abnormal changes in , which aggravate the disease progression and trigger complications.

To improve diabetes mellitus and its chronic complications, therefore, improvement of growth hormone/insulin-like growth factor 1 axis anomalies is one of the treatment strategies.

A new study by the research group of Dr. Chen shows that sericin can significantly decrease the blood glucose levels of the diabetic rats, and alleviate diabetic hippocampal damage through improving disorders in the growth hormone/insulin-like growth factor 1. These results are published in (Vol. 8, No. 19, 2013).

Article: ” Effect of sericin on diabetic hippocampal growth hormone/insulin-like growth factor 1 axis,” by Zhihong Chen, Songhe Yang, Yaqiang He, Chengjun Song, Yongping Liu.

Source

Neural Regen Res. 2013;8(19):1756-1764.

Neural Regeneration Research