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Eating less salt may reduce the risk of stomach cancer: UEG calls for greater salt-awareness across Europe

Stomach cancer is diagnosed in around 80,000 people in the European Union (EU) each year1 and is associated with a very poor prognosis. The most well-established risk factor for stomach cancer is infection with Helicobacter pylori (H. pylori), which causes inflammation within the stomach that can progress to stomach cancer.

Now scientists believe that eating too much salt also increases the risk of stomach cancer, with a direct relationship found between salt consumption and cancer risk.2 According to Professor John Atherton, UEG Secretary General and a leading H. pylori expert, the combination of H. pylori infection and a high salt intake appears to be especially dangerous. “Although we don’t know exactly why salt increases the risk of stomach cancer, studies suggest that it may encourage the growth of H. pylori and make it more toxic to the cells of the stomach,” he says.

Stomach cancer in the EU

The recent Survey of Digestive Health Across Europe3 reported that more than 80,000 new cases of stomach cancer were identified in the EU in 2012, with twice as many men as women affected.1 H. pylori infection, which typically occurs during childhood and is difficult to detect, has been estimated to be responsible for around three-quarters of all stomach cancers.3 Excessive salt consumption is thought to contribute to a quarter of all cases.4

“Most of us know that salt is associated with high blood pressure and an increased risk of heart disease and stroke,” says Prof. Atherton. “However, I suspect very few people are aware that a high-salt diet may also increase the risk of stomach cancer.”

Salt consumption guidelines

The European Commission and many individual European countries have taken positive action towards reducing salt consumption across the continent. Current guidelines from the World Health Organisation (WHO) suggest that no more than 5 g of salt (less than 1 teaspoon) should be eaten per day – a challenging target given that most salt in our diets is not added by us, but comes from processed foods such as bread, cheese, breakfast cereals and ready meals.

“In the UK, our salt target for adults is no more than 6 g per day, which should theoretically reduce the risk of stomach cancer as well as other salt-related health problems,” says Prof. Atherton. “Although we need more studies to confirm that eating a low-salt diet reduces the incidence of stomach cancer, there is preliminary evidence from Japan5 to suggest this would be the case.”

It is straightforward to reduce salt in your diet: take special care when shopping to, buy low-salt versions of your favourite foods; moderate your intake of some foods such as cured meat, bread, cheese and table sauces; and to add no salt during cooking or at the table.6 This will reduce your risk of a variety of diseases, particularly heart disease and stroke and it now looks as though it will also reduce your risk of developing stomach cancer.

Source

1. WHO International Agency for Research on Cancer. http://eu-cancer.iarc.fr/.

2. D’Elia L, Rossi G, Ippolito R, et al. Clin Nutr 2012;31(4):489-98.

3. Roberts SE, Samuel DG, Williams JG, et al. Survey of Digestive Health across Europe. Part one: The burden of gastrointestinal diseases and the organisation and delivery of gastroenterology services across Europe. Report for United European Gastroenterology. August 2014.

4. Parkin DM. Br J Cancer 2011;105:S31-S33.

5. Tominaga S, Kuroishi T. Int J Cancer 1997;10(Suppl):2-6.

6. World Action on Salt & Health. Salt and stomach cancer. Available at: http://www.worldactiononsalt.com/salthealth/factsheets/stomach/index.html. Last accessed 5 January 2015.

Source: United European Gastroenterology (UEG)