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Entry route of virus affects response to viral infections

Insects can transmit to humans. Therefore, understanding how insects cope with , and what are triggered, can be important to stop diseases transmission. In a study published in the scientific journal PLOS Pathogens, researchers from the Instituto Gulbenkian de Ciencia (IGC; ) now show that the entry route of the how the insect host responds to it. Using the fruit flies as a model of study, they discovered an immune mechanism that is specifically effective when flies are infected through feeding.

[Fruit Fly Digestive Tract Cells Infected with Virus.]
Insect muscle cells are marked in red, cell nuclei (DNA) in blue and virus in green.
Credit: Alvaro Gil Ferreira (IGC)


This research was carried out at in collaboration with the University of Cambridge. This study was funded by Biotechnology and Biological Sciences Research Council (UK) and Fundação para a Ciência e Tecnologia (Portugal).

Instituto Gulbenkian de Ciencia