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Errant gene turns cells into mobile cancer factories

Salk scientists find key that underlies deadly behavior in hard-to-treat

Salk Scientists Find Molecular Mechanism that Underlies Metastatic Breast Cancer
New Salk research shows that high levels of the critical gene Sox10 is tied to aggressive breast cancer. In parts of the adult , Sox10 is expressed in cells with higher levels of and not in that lack detectable stem cell activity. Progesterone receptor (red) indicates non-stem-like , which show an inverse correlation with cells expressing Sox10 (blue). A protein called cytokeratin-8 (green) shows the development of the gland.
Credit: Salk Institute