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Extra Weight Linked To Better Outcomes For Septic Shock, Asthma Exacerbation

Although obesity is linked to a variety of health risks, new research indicates that patients may have an advantage over patients in certain health situations, including and acute asthma exacerbation.

In two separate studies presented at 2012, the annual meeting of the , researchers compared outcomes in obese (BMI >30) vs nonobese patients with either septic shock or acute asthma exacerbation. Results showed that, although with asthma are more at risk for asthma exacerbations, near fatal exacerbations were more prevalent in nonobese patients.

Likewise, obese patients with septic shock had decreased mortality compared with nonobese patients. Researchers attribute this “obesity paradox” partly to a blunted pro-inflammatory cytokine response in obese patients.


This study was presented during CHEST 2012, the annual meeting of the American College of Chest Physicians, held October 20 – 25, in Atlanta, Georgia.
American College of Chest Physicians