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Fighting a worm with its own genome

Hints for how to improve the treatment of might lie within the parasite’s own

A 19-Day-post-Infection Male Ancylostoma ceylanicum
Tiny parasitic hookworms infect nearly half a billion people worldwide — almost exclusively in — causing health problems ranging from gastrointestinal issues to and stunted growth in children. By sequencing and analyzing the of species Ancylostoma ceylanicum, Caltech researchers have uncovered new information that could aid the fight against these parasites. The results of their work were published online in the March 2, 2015, issue of the journal Nature Genetics.
Credit: Yan Hu/Aroian Lab/UC San Diego


The genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families. Nature Genetics(2015)doi:10.1038/ng.3237

California Institute of Technology