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For Metastatic Melanoma, Should High-Dose Interleukin-2 Continue To Be The Treatment Of Choice?

Administering high-doses of interleukin-2 (IL-2) has been the preferred treatment for patients with stage IV melanoma. An article published in the current issue of and Radiopharmaceuticals, a peer-reviewed journal from Mary Ann Liebert, Inc., explores whether or not this regimen is still the most effective. The article is available free online at the Cancer Biotherapy and Radiopharmaceuticals website.*

In the article “Should High-Dose Interleukin-2 Still Be the Preferred Treatment for Patients with ?” ** and colleagues at the Hoag Institute for Research and Education and Hoag Family Cancer Institute, Newport Beach, CA concluded that until long-term survival data for some of the newer drugs are available, patients with stage IV metastatic melanoma who are well enough to be given intensive IL-2 therapy should receive it initially, either alone or in combination with one of the newer therapeutic agents.

“This is an important article that puts into perspective the reasons why IL-2 should continue to be the initial therapy in patients with metastatic melanoma,” says , PhD, Division of Radiation Biology, , University of Alabama at Birmingham.


* http://www.liebertpub.com/cbr
** http://online.liebertpub.com/doi/full/10.1089/cbr.2012.1220
Mary Ann Liebert, Inc./Genetic Engineering News