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For seizure control, PQ disconnection with the activity of isolated PTO nerve tissue

Diffuse lesions involving the posterior quadrant (PQ) of the cerebral hemisphere (temporal, , and ) induce .

These patients are potential candidates for .

Maintenance of isolated activity after surgery plays a crucial role in the neuroprotective effects of neurosurgery treatment.

Shaoya Yin and colleagues from Tianjin Huanhu Hospital in China selected two patients with temporal-parietal-occipital (PTO) intractable epilepsy to receive posterior quadrant disconnection.

Postoperative MRI scans of the two epileptic patients showed that the disconnected brain tissue still survived, the activity of temporal-parietal occipital nerve tissue was maintained, and nerve fibers were completely disconnected.

The involved patients were followed-up for over 1 year after surgery, during which time the epilepsy was completely controlled.

The relevant paper has been published in (Vol. 9, No. 4, 2014).


Neural Regeneration Research