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Gateway to the brain – Scientists harness nature’s transport system to the brain

Scientists from Duke-NUS Medical School (Duke-NUS) have derived a structural model of a transporter at the blood-brain barrier called Mfsd2a.1 This is the first molecular model of this critical transporter, and could prove important for the development of therapeutic agents that need to be delivered to the brain – across the blood-brain barrier. In future, this could help treat neurological disorders such as glioblastoma.

Gateway to the Brain
This image shows the structural model of critical transporter, Mfsd2a.
Credit: Duke-NUS Medical School