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How our bodies keep unwelcome visitors out of cell nuclei

The structure of pores found in has been uncovered by a -led team of scientists, revealing how they selectively block certain molecules from entering, protecting genetic material and normal cell functions. The discovery could lead to the development of new drugs against viruses that target the and new ways of delivering gene therapies, say the scientists behind the study.

[Nuclear Pores]
These are imaged by atomic force microscopy, appearing as a craterlike landscape in which each crater corresponds to a pore of ~100 nm diameter.
Credit: UCL


The team included researchers from across UCL, alongside collaborators at Birkbeck, University of London and the University of M√ľnster, Germany.

University College London