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In 200-Mile Long Mountain Race, Runners’ Muscles Protected By Sleep Deprivation, Pacing

Runners who complete one of the world’s most challenging ultra-marathons experience less , and compared to those who run distances half to one quarter as long, according to the results of research published in the open access journal PLOS ONE by and colleagues from the University of Lausanne, Switzerland.

The researchers tested the effects of as well as blood and muscle markers of inflammation in runners who completed the , an over 200-mile mountain ultramarathon with 24,000 m of elevation changes. Compared to participants at a shorter Alpine ultra-marathon approximately 103 miles in length, runners at had fewer alterations in neuromuscular functions and lower levels of muscle damage and inflammation, despite running nearly double the distance.

The authors suggest that protective pacing strategies employed by these runners in the first half of the race, combined with sleep deprivation effects in the second half may induce a relative muscle preservation process.


Citation: Saugy J, Place N, Millet GY, Degache F, Schena F, et al. (2013) Alterations of Neuromuscular Function after the World’s Most Challenging Mountain Ultra-Marathon. PLoS ONE 8(6): e65596. doi:10.1371/journal.pone.0065596

Financial Disclosure: The authors have no funding or support to report.

Competing Interest Statement: The authors have declared that no competing interests exist.

LINK TO THE SCIENTIFIC ARTICLE: http://dx.plos.org/10.1371/journal.pone.0065596

Public Library of Science