CDK6 is needed for leukemic stem cell activation (left). When CDK6 is absent, the LSC remains in a quiescent state and leukemia formation is prohibited (right).
Credit:Angelika Berger / Vetmeduni Vienna
Service: The article ‘CDK6 as a key regulator of hematopoietic and leukemic stem cell activation‘ by Scheicher R, Hoelbl-Kovacic A, Bellutti F, Tigan AS, Prchal-Murphy M, Heller G, Schneckenleithner C, Salazar-Roa M, Zöchbauer-Müller S, Zuber J, Malumbres M, Kollmann K and Sexl V. was published in the journal Blood. DOI: 10.1182/blood-2014-06-584417