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Lasers used to spatially and temporally control the release of a tagged protein inside a cell

Optogenetics, which uses light to control , is poised to become an important technology in and beyond. The in UC Santa Barbara’s Department of Chemistry and Biochemistry has made a major contribution to this emergent field by developing a light-activated nanocarrier that transports proteins into cells and releases them on command. The findings appear in the journal Molecular Pharmaceutics.

A Hollow Gold Nanoshell with a Modular Nickel Linking Layer Exposed to a Laser
A hollow gold nanoshell with a modular nickel linking layer (upper left) exposed to a laser (800 nm) shows the cellular uptake and release.


University of California – Santa Barbara