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Making Engineered Cartilage Stronger

Lab-grown tissues could one day provide new treatments for injuries and damage to the joints, including , .

[Making Engineered Cartilage Stronger]
Connective tissues like cartilage are made of cross-linked bundles of collagen fibers. biomedical engineers have discovered that reducing oxygen or adding an enzyme called LOX can make these bundles stronger. The technique can be used to strengthen both natural cartilage kept in the lab for transplant, and artificial cartilage grown in culture.
Credit: and , UC Davis


Other authors on the paper are , Nikolaos Paschos and Jerry Hu, all at the Department of Biomedical Engineering. Funding was provided by the National Institutes of Health.

University of California – Davis