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Mass. General study points to the first topical treatment for common benign skin lesions

An investigation into the molecular mechanisms responsible for the most common type of benign skin lesion may lead to the first nonsurgical treatment for the growths called seborrheic keratoses (SKs), which in addition to being cosmetically unattractive are often worrisome to patients. A paper by Massachusetts General Hospital (MGH) researchers, published online in the Journal of Investigative Dermatology, reports that blocking the action of a specific signaling enzyme leads to the death of cultured SK cells and the breakdown of SK lesions.

Seborrheic keratosis lesions
This is a picture of Seborrheic keratosis lesions on a patient’s back.
Credit: James Heilman, MD, via Wikimedia Commons