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Memory problems caused by sleep deprivation prevented in mice

Sleep is a for , and most people don’t get enough. Research has shown that even brief periods of can lead to deficits in .

[Targeting the Hippocampus in Sleep Deprivation]
The hippocampus of a mouse in the study glows green where cells have taken up a receptor that triggers a cAMP signalling pathway. After administering the ligand to the receptor, researchers could selectively boost cAMP levels in this region and this cell type only. They found that ‘rescuing’ these cells with a shot of cAMP preventing the that sleep loss can induce.
Credit: University of Pennsylvania


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University of Pennsylvania