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Most commonly used TB test fails to accurately diagnose pregnant HIV positive women

New research finds that the most commonly used test for tuberculosis fails to accurately diagnose TB in up to 50 percent of pregnant women who are HIV+. The research published early online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine is believed to be the first study to compare the accuracy of two TB tests – the Quantiferon Gold In Tube® blood test and the more commonly used TST or tuberculin skin test–in this population. The study “Quantitative IFN-, IL-2 Response and Latent Tuberculosis Test Discordance in HIV-infected Pregnant Women” is also the first study to examine pregnancy’s effect on the body’s response to TB.

TB Diagnosis in Pregnant HIV Positive Women
This is a TB infected lung.
Credit: ATS