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Motor relearning program improves neurological function of brain ischemia

The motor relearning program can significantly improve various functional disturbance induced by ischemic cerebrovascular diseases. However, its mechanism of action remains poorly understood.

According to a study published in (Vol. 8, No. 16, 2013), models of ischemic brain injury in the rhesus macaque were induced by electrocoagulation of the M1 segment of the right middle cerebral artery, then the motor relearning program was after model establishment.

Glial fibrillary acidic protein and neurofilament protein expression changes could reflect the repair status of damaged neurons and astrocytes, while vascular endothelial growth factor and basic fibroblast growth factor could reflect angiogenesis in damaged brain tissue.

Researchers found that the motor relearning program significantly promoted neuronal regeneration, repair and angiogenesis in the surroundings of the infarcted hemisphere, and improve in the rhesus macaque following , which provides a new theoretical idea for the clinical treatment of .

Source

Article: ” How does the motor relearning program improve neurological function of brain ischemia monkeys?” by Yong Yin1, Zhen Gu2, Lei Pan1, Lu Gan1, Dongdong Qin3, Bo Yang4, Jin Guo5, Xintian Hu3, Tinghua Wang6, Zhongtang Feng6 (1 Department of Rehabilitation Medicine, Fourth Hospital of Medical University, 650021, Yunnan Province, China; 2 Department of Neurosurgery, Fourth Hospital of Medical University, 650021, Yunnan Province, China; 3 Institute of Zoology, Chinese Academy of Sciences, 650223, Yunnan Province, China; 4 Department of Nuclear Medicine, Fourth Hospital of Medical University, 650021, Yunnan Province, China; 5 Department of Pathology, Fourth Hospital of Medical University, 650021, Yunnan Province, China; 6 Institute of Neuroscience, Medical University, 650500, Yunnan Province, China)

Yin Y, Gu Z, Pan L, Gan L, Qin DD, Yang B, Guo J, Hu XT, Wang TH, Feng ZT. How does the motor relearning program improve neurological function of brain ischemia monkeys? Neural Regen Res.

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Neural Regeneration Research