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New computer program can help uncover hidden genomic alterations that drive cancers

Cancer is rarely the result of a single mutation in a single gene. Rather, tumors arise from the complex interplay between any number of mutually exclusive abnormal changes in the genome, the combinations of which can be unique to each individual patient. To better characterize the functional context of genomic variations in cancer, researchers at University of California San Diego School of Medicine and the Broad Institute developed a new computer algorithm they call REVEALER.

REVEALER
To better characterize the functional context of genomic variations in cancer, researchers developed a new computer algorithm called REVEALER.
Credit: UC San Diego Health