Johns Hopkins engineers have invented a lab device to give cancer researchers an unprecedented microscopic look at metastasis, the complex way that tumor cells spread through the body, causing more than 90 percent of cancer-related deaths. By shedding light on precisely how tumor cells travel, the device could uncover new ways to keep cancer in check.
This dish houses a lab chip that Johns Hopkins engineers built to gain an unprecedented closeup view of how cancer cells enter the bloodstream to spread the disease.
Photo by Will Kirk/Johns Hopkins University.
Wong’s work has been supported by an INBT training grant. Development of the cancer research device was supported by National Institutes of Health grant number R01CA170629.
Live-Cell Imaging of Invasion and Intravasation in an Artificial Microvessel Platform. Published OnlineFirst June 26, 2014; doi: 10.1158/0008-5472.CAN-14-1042 Cancer Res September 1, 2014 74; 4937