Marked by yellow tags, the tiny particles released by this bacterium may help initiate inflammatory bowel disease, according to new research from Washington University School of Medicine in St. Louis.
Credit: Wandy Beatty
The research was supported by the the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH), grant DK097079, and the National Institute of Child Health and Human Development, also of the NIH, via the Pediatric Physician Scientist Program.
Hickey CA, Kuhn KA, Donermeyer DL, Porter NT, Jin C, Cameron EA, Jung H, Kaiko GE, Wegorzewska M, Malvin NP, Glowacki R, Hansson GC, Allen PM, Martens EC, Stappenbeck TS. Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles. Cell Host & Microbe, online May 13, 2015. DOI: 10.1016/j.chom.2015.04.002