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New nanoparticle technology to decipher structure and function of membrane proteins

Researchers at Karolinska Institutet, Sweden, have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment. The method, described in Nature Methods, makes it possible to access drug targets that previously could not be investigated and therefore potentially allows for the development of novel drugs, therapeutic antibodies and vaccines.

Illustration Salipro System
According to the researchers, the new Salipro technology may offer a wide range of potential applications; from structural biology to the discovery of new pharmacological agents.
Credit: Jens Frauenfeld et al.