TCGA tumor genome sequencing analyses offer new insights into the effects of HPV and smoking, and find genomic similarities with other cancers
TCGA researchers have uncovered new details about the potential role of the human papillomavirus in head and neck cancers. HPV-related head and neck cancers have been growing in number.
Credit:Ernesto del Aguila, NHGRI
This work was supported by the following NIH grants: P50CA097190, P50CA16672, U54 HG003273, U54 HG003067, U54 HG003079, U24 CA143799, U24 CA143835, U24 CA143840, U24 CA143843, U24 CA143845, U24 CA143848, U24 CA143858, U24 CA143866, U24 CA143867, U24 CA143882, U24 CA143883, U24 CA144025 and RO1 CA 095419. Additional funding was provided by the Bobby F. Garrett Fund for Head and Neck Cancer Research and the National Institute on Deafness and other Communication Disorders (NIDCD) Intramural Projects ZIA-DC-000016, 73 and 74.
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. Online January 28, 2015. DOI: 10.1038/nature14129.