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Patients with major depressive disorder exhibit abnormal activation of the occipital lobes

A recent study published in the (Vol. 8, No. 18, 2013) combined cognition tasks and functional MRI, and designed multiple repeated event-related tasks; additionally, using the International Affective Picture System-based event-related tasks, this study investigated brain functional characteristics of patients exhibiting, negative bias brain imaging changes and cognitive dysfunction, as well as their relationship based on biased quantitative data.

Results show that:

  1. the number of error responses was calculated to identify bias of emotion recognition between patients with major depressive disorder and normal controls, suggesting that the depressed patients exhibited negative bias towards emotion task stimuli based on quantitative data;
  2. the activation of the was attenuated in depressed patients when doing emotion tasks;
  3. Deficits in the may be an initiating factor for depression onset, which results in attention deficit disorder and cognitive dysfunction.

Source

Article: ” Abnormal activation of the occipital lobes during emotion picture processing in major depressive disorder patients,” by Jianying Li1, Cheng Xu2, Xiaohua Cao1, Qiang Gao2, Yan Wang1, Yanfang Wang1, Juyi Peng1, Kerang Zhang1 (1 Department of Mental Health, First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China; 2 MRI Room, Shanxi Provincial People’s Hospital, Taiyuan 030012, Shanxi Province, China)

Li JY, Xu C, Cao XH, Gao Q, Wang Y, Wang YF, Peng JY, Zhang KR. Abnormal activation of the occipital lobes during emotion picture processing in major depressive disorder patients. Neural Regen Res. 2013;8(18):1693-1701.

Full text: http://www.sjzsyj.org:8080/Jweb_sjzs/CN/article/downloadArticleFile.do?attachType=PDF&id=638

Neural Regeneration Research