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Potential To Improve Human Cancer Studies Using Novel Pig Model

A naturally occurring line of pigs can support the growth of injected under their skin, offering a promising new large animal model for studying human cancers and testing new drugs and treatment strategies. The ability of and pancreatic carcinoma cells to grow in these pig models is described in an article in BioResearch Open Access, a new bimonthly peer-reviewed open access journal from , Inc.. The article is available free online at the BioResearch Open Access website.*

Mathew Basel and colleagues, Kansas State University (Manhattan, KS) and (Ames), highlight the advantages that pig disease models offer, as they are anatomically and physiologically more closely related to humans than traditional rodent animal models. As a result, findings from studies in large animal models such as pigs are more likely to translate into similar outcomes in humans. The authors present their findings in the article “ Are Not Rejected in a Naturally Occurring Immunodeficient Porcine Line: A Human Tumor Model in Pigs.” **

“This novel animal model has the potential to become a highly useful model in cancer research studies, in addition to providing significant opportunities for drug discovery and other translational applications,” says Editor-in-Chief Jane Taylor, PhD, MRC Centre for Regenerative Medicine, University of Edinburgh, Scotland.


* http://www.liebertpub.com/biores
Mary Ann Liebert, Inc./Genetic Engineering News