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Reducing drug costs for patients could improve outcomes for high blood pressure

Expanding and reducing drug costs that are paid by patients (drug co-payments) in countries without universal free healthcare, such as the United States, may improve the treatment, and control of (, a condition which affects one billion people worldwide and leads to 7.5 million deaths), according to a study by UK and Canadian researchers published in this week’s PLOS Medicine.

Will Maimaris from the London School of Hygiene & Tropical Medicine and colleagues from the and McMaster University in Canada reviewed 53 published studies and found an association between reduced co-payments for , including for medications, and improved hypertension control and treatment adherence in multiple US studies, and in studies from Finland, Israel, and Brazil.

The authors also found that in US settings, coverage and having a routine physician or place of care were linked to improved hypertension outcomes.

However, in their review, the authors found that there were few studies in low-and middle-income countries, which bear most of the global burden of hypertension, and also that there is an urgent need for studies that evaluate how aspects of health care systems other than financing (such as delivery and governance mechanisms) and interactions between health care system arrangements affect hypertension outcomes. The authors argue that without the results of such studies, governments and national and international organizations will not know the best ways to deal effectively with the global public-health crisis posed by hypertension.

The authors say: “This review supports the minimization of medication co-payments in health insurance plans, and although studies were largely conducted in the US, the principle is likely to apply more generally.”

They add: “Studies that identify and analyse complexities and links between health systems arrangements and their effects on hypertension management are required, particularly in low-and middle-income countries.”


Funding: This research was part of the HOPE-4 project. This part of the HOPE-4 project was funded by the Canadian Institutes of Health Research with an award number IHR-120389. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: The authors have declared that no competing interests exist.

Citation: Maimaris W, Paty J, Perel P, Legido-Quigley H, Balabanova D, et al. (2013) The Influence of Health Systems on Hypertension Awareness, Treatment, and Control: A Systematic Literature Review. PLoS Med 10(7): e1001490. doi:10.1371/journal.pmed.1001490

Public Library of Science