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Research shows England’s use of antidepressants rising faster than ever since the start of the recession

The financial crisis and subsequent recession saw a significant acceleration in the numbers of prescribed by GPs, new new research published by the reveals.

The study shows that between 1998 and 2012, the amount of antidepressants dispensed in the community each year rose by 25 million – from 15 million items in 1998, to 40 million in 2012. Almost half of that increase occurred in the four years between the 2008 financial crisis and 2012, the last year for which data are available. This means that the annual rise in prescriptions has risen to 8.5% per year since the banking crash, compared to 6.7% before.

This striking increase is despite the incidence of depression having risen much more slowly over the same time period, meaning that either antidepressants were heavily under-prescribed in 1998, or they are heavily overprescribed now. Some GP practices also prescribed far more medicine than others even where their patients were similar – suggesting over-use or under-use in many parts of England.

The research is published as part of the and Health Foundation’s QualityWatch programme, which is tracking the quality of health and social care in England.

Examining the number of tablets dispensed on NHS prescriptions across the country, Nuffield Trust researchers found that:

  • Areas with more white people, more women, and more people over the age of 65, had the heaviest use of antidepressants. Areas with more men and more people from ethnic minorities, on the other hand, had significantly lighter use.
  • Even when regional characteristics are taken into account, there is significant variation in the rates of antidepressant prescription across the country. For example, per 1000 people, residents of Blackpool collected more than four times as many of these tablets each month as those of the London Borough of Brent.
  • An analysis of changes over time found that increases in unemployment were associated with significant increases in the number of anti-depressant tablets dispensed. A 1% rise in unemployment typically meant one and a half more tablets were given out per person on a GP list, per year.
  • An analysis comparing practices in different geographical areas, meanwhile, did not show clear links to unemployment – but areas with worse housing tended to see significantly higher antidepressant use.
  • GPs who prescribe more antibiotics also tend to prescribe more antidepressants, suggesting doctors vary across the board in how likely they are to use drugs to deal with their patients’ conditions.
  • Adjusting for all these factors, younger, female GPs who qualified in the UK tend to prescribe more anti-depressants to their patients.

Adam Roberts, Senior Research Analyst at the Nuffield Trust, said:

“It’s striking that GPs were prescribing an extra 2.7 million antidepressants in 2012, compared to the trend we saw during the years of economic growth. That acceleration in the use of these drugs raises some difficult questions about the impact that poverty and unemployment can have on people’s health.

“Our research shows stark variation in antidepressant prescription rates between regions, ethnicities and age groups. While some variation is to be expected, the differences between regions suggest that there could be particular underlying problems in mental health for people in areas suffering from unemployment and poor housing.

“What we don’t know from the research is what level of prescribing is objectively the ‘right’ level. But the fact that the rise over time outstrips the incidence of depression suggests either that we were dispensing far too few of these drugs in 1998, or that we are dispensing far too many now.”

Professor Nick Barber, Director of Research at the Health Foundation, said:

“The report clearly shows a significant increase in antidepressant prescriptions in recent years. A crucial finding for doctors and patients to consider is that there is real variation in prescription rates across GP practices.

“These differences imply that certain practices have a propensity to over or under prescribe. This could suggest that not enough attention has been given to individual patients’ needs, including the need to avoid possible side effects of these medicines.”


Nuffield Trust