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Scientists coax stem cells to form 3-D mini lungs

Human lung organoids will help scientists learn more about lung diseases, test new drugs

Lung Organoid
Scientists, led by the , coax to form mini lungs, 3-D structures that mimic and survived in the lab for 100 days.


The research has gained support from the National Heart, Lung and Blood Institute (NHLBI), the and Kidney Diseases (NIDDK), the March of Dimes and the U-M’s Center for Organogenesis and Biological Sciences Scholars Program (BSSP).

Reference: “In vitro generation of human pluripotent stem cell derived lung organoids,” eLife, DOI:10.7554/eLife.05098.001

University of Michigan Health System