Researchers have cracked a code that governs infections by a major group of viruses including the common cold and polio.
A code hidden in the arrangement of the genetic information of single-stranded RNA viruses tells the virus how to pack itself within its outer shell of proteins.
Credit:University of Leeds
The research was funded by the Biotechnology and Biological Sciences Research Council (BBSRC), the Engineering and Physical Sciences Research Council (EPSRC). Professor Twarock’s Royal Society Leverhulme Trust Senior Research Fellowship and Dr Dykeman’s Leverhulme Trust Early Career Fellowship also supported the work.
The full paper: N. Patel et al. ‘Revealing the density of encoded functions in a viral RNA,’ PNAS (2014); DOI 10.1073/ pnas.1420812112).