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Scientists reveal trigger mechanism for recovery after spinal cord injury

After an incomplete , the body can partially recover basic motor function. So-called muscle spindles and associated sensory circuits back to the spinal cord promote the establishment of novel neuronal connections after injury. This circuit-level mechanism behind the process of motor recovery was elucidated by Prof. ’s research group at the Biozentrum, and the . Their findings may contribute to designing novel strategies for treatment after and have now been published in the journal Cell.

Muscle Spindle
This shows the sensory nerve terminals (orange) of a .
Illustration: University of Basel, Biozentrum


Original citation:

Aya Takeoka, Isabel Vollenweider, Grégoire Courtine, and Silvia Arber Muscle Spindle Feedback Directs Locomotor Recovery and Circuit Reorganization after Spinal Cord Injury Cell (2014)

University of Basel