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Second-Line Defense Needed For Patients With NSCLC

In lung cancer, patients who benefit from drugs like will inevitably develop drug resistance. This is heralded by cancer growth and increasing tumor-related symptoms. Now scientists are investigating a second line of defense by studying the use of the novel AKT inhibitor MK-2206 in combination with for patients whose benefit from has begun to wane. Results of a will be presented during the 5th on Lung Cancer.

Dr. , medical oncologist and professor of medicine at the University of California Davis Comprehensive Cancer Center in Sacramento, U.S.A, will share the latest on this research at an abstract session Friday, July 27 at 8 a.m. in the Louvre I & II rooms at the Hotel.

Dr. Lara will present the initial efficacy and toxicity analysis of a stratified phase II trial of MK2206 plus erlotinib in two patient cohorts: those tumors with or without activating EGFR mutations. The trial, sponsored by the through the California Cancer Consortium, has enrolled 42 patients with advanced NSCLC who have had prior benefit from erlotinib (either response or stable disease for at least 12 weeks) but have since progressed.

The 5th Latin American Conference on Lung Cancer will highlight the latest in lung cancer research and tobacco control. Nearly 1,000 medical professionals will gather at the conference to discuss the latest lung cancer research and treatment. Lung cancer kills more than 1.5 million people each year worldwide. It is also among the most challenging cancers to treat.

Source

International Association for the Study of Lung Cancer