Finding provides new therapeutic target for prion diseases
Prion protein aggregates (brown) in the brain of a mouse expressing the human-elk protein.
Credit: UC San Diego School of Medicine
Co-authors of this study include Timothy D. Kurt, Cyrus Bett, Jun Liu, Tom Yang, UC San Diego; Lin Jiang, David Eisenberg, UC Los Angeles and Howard Hughes Medical Institute; Natalia Fernández-Borges, CIC bioGUNE, Spain; Terry R. Spraker, Colorado State University, Fort Collins; Joaquín Castilla, CIC bioGUNE and Basque Foundation for Science, Spain; and Qingzhong Kong, Case Western Reserve University.
This research was funded, in part, by the National Institutes of Health (grants NS055116, NS069566, U54AI0359 and AG029430), national grants from Spain and the Morris Animal Foundation.