- Dopamine releasing cells in the forebrain are difficult to access in most vertebrates so the researchers examined transparent hatchling zebrafish
- They used a technique called electrophysiology to capture electrical signals from dopamine neurons in the forebrain whist simultaneously observing motor activity in the spinal cord
- Research could impact on understanding of conditions such as schizophrenia and Parkinson’s disease
Scientists studying hatchling fish have made a new advance in studying a chemical in the brain that impacts on movement.
The team from the University of Leicester Department of Biology has examined transparent hatchling zebrafish to gain new insights into the working of neurons in areas of the brain that are normally difficult to access.
This zebrafish image depicts an antibody labelled spinally-projecting dopaminergic neurons in the forebrain of a hatchling zebrafish.
Credit:University of Leicester
Firing Dynamics and Modulatory Actions of Supraspinal Dopaminergic Neurons during Zebrafish Locomotor Behavior, DOI: 10.1016/j.cub.2014.12.033