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Study reveals possible treatment for diseases caused by Mitofusin 2 deficiency

Researchers have discovered a novel role for Mitofusin 2, and the findings may point to a new treatment for patients with caused by loss of the . The study appears in The Journal of Cell Biology.

Mfn2-deficient Mitochondria
In mice, mitochondria (green) in healthy (left) and Mfn1-deficient (center) are organized in a linear arrangement, but the organelles are enlarged and disorganized in Mfn2-deficient cells (right).
Credit: Mourier et al., 2015


Source

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels Mourier, A., et al. 2015. J. Cell Biol. doi:10.1083/jcb.201411100.

Rockefeller University Press