A University of South Florida College of Public Health professor and his team of researchers have become the first to uncover part of the mysterious process by which malaria-related parasites spread at explosive and deadly rates inside humans and other animals.
In the dividing Toxoplasma tachyzoite (left cartoon), the spatial segregation of novel extranuclear bipartite core structures (outer core, red; inner core, green) of the centrosome is well resolved and aligned with the nuclear centromeres (blue) as captured by super-resolution microscopy.
Credit: High-resolution image by Dr. Maria Francia
The study was supported by a grant from the National Institute of Allergies and Infectioius Disease (NAID), National Institutes of Health.
“A Novel Bipartite Centrosome Coordinates the Apicomplexan Cell Cycle,” Elena S. Suvorova, Maria Francia, Boris Striepen and Michael W. White, PLOS Biology, March 3, 2015; DOI:10.1371/journal.pbio.1002093.