Children who suffer from Hutchinson-Gilford Progeria Syndrome (HGPS) age prematurely due to a defective protein in their cells.
The image shows two cell nuclei containing human DNA (blue). Because of the large quantity of progerin (red), the nuclei in the cells of HGPS patients (left) are deformed in comparison to nuclei with very low levels of progerin (right).
Credit: Photo: K. Djabali / TUM
Original publication: Gabriel D., Roedl D., Gordon L. B. and K. Djabali, Sulforaphane enhances progerin clearance in Hutchinson–Gilford progeria fibroblasts, Aging Cell, 2014. DOI: 10.1111/acel.12300