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Support cells in the brain offer a new strategy to boost memory

Researchers from the have uncovered a new memory regulator in the brain involving , which may offer a potential treatment to improve memory in Alzheimer’s disease

Mouse Model of Alzheimer's Disease
Astrocytes are stained in red, the A2A receptors in green, the overlap between the two shows as yellow, and the cell nuclei are in blue.
Credit:Anna Orr/Gladstone Institutes


Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory, doi:10.1038/nn.3930

Other researchers on the study include Max Wang, , , Xin Wang, , Jing Kang, Gui-Qiu Yu, Edward Hsiao, Nino Devidze, Dena Dubal, and Bruce Conklin from the Gladstone Institutes, and Anthony Adame and Eliezer Masliah from the University of California, San Diego. Funding was provided by the , the MetLife Foundation, and the National Center for Research Resources.

Gladstone Institutes