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Systematic review: Cinnamon may be beneficial for diabetic patients but dosing uncertain

Consumption of is associated with a statistically significant decrease in levels of fasting , total , low-density lipoprotein and triglyceride, and an increase in high-density lipoprotein .

A meta-analysis of 10 randomized controlled trials evaluating the effects of cinnamon use in 543 patients with type 2 diabetes at doses of 120 mg/d to 6 g/d for four to 18 weeks found reduced levels of fasting plasma glucose (-24.6 mg/dL; 95 percent CI, -40.5 to -8.7), total cholesterol (-15.6 mg/dL, -29.8 to -1.4), LDL-C (-9.4 mg/dL; 95 percent CI, -17.2 to -1.6) and triglycerides (-29.6 mg/dL; 95 percent CI, -48.3 to -10.9). Cinnamon also increased levels of HDL-C (1.7mg/dL; 95 percent CI, 1.1 to 2.2). No significant effect on was seen. High degrees of heterogeneity were present for all analyses except HDL-C.

Despite the generally positive results, the authors advise caution in applying the results of this analysis to patient care because of the uncertainty of the dose and duration of cinnamon use and uncertainty of the ideal patient population.

Cinnamon Use in Type 2 Diabetes: An Updated Systematic Review and Meta-Analysis
http://www.annfammed.org/content/11/5/452.full
By Olivia J. Phung, PharmD, et al
Western University of Health Sciences, Pomona, Calif.

Source

September/October 2013 Annals of Family Medicine

American Academy of Family Physicians