3 days popular7 days popular1 month popular3 months popular

Digital ‘Rosetta Stone’ decrypts how mutations rewire cancer cells

Scientists have discovered how genetic cancer mutations systematically attack the networks controlling human cells, knowledge critical for the future development of personalized precision cancer treatments. Since the human genome was decoded more than a decade ago, cancer genomics studies have dominated life science worldwide and have been extremely successful at identifying mutations in individual patients [...]

Which patients will respond to melanoma immunotherapy?

Patients with metastatic melanoma who have benefited from a new type of cancer immunotherapy don’t appear to share the same tumor-produced antigens, according to a new report by Eliezer Van Allen and colleagues. If the molecular targets for the immunotherapy differ from patient to patient, as this study suggests, it may be difficult to predict [...]

Cancer discovery links experimental vaccine and biological treatment

A new study at the University of Wisconsin-Madison has linked two seemingly unrelated cancer treatments that are both now being tested in clinical trials. One treatment is a vaccine that targets a structure on the outside of cancer cells, while the other is an altered enzyme that breaks apart RNA and causes the cell to [...]

Danish researchers map important enzyme in the fight against cancer

Researchers from the University of Copenhagen have discovered what regulates an enzyme that is central to the growth of cancer tumours. This could be of great value to future cancer treatment. Danish researchers from the University of Copenhagen have discovered what controls the enzyme that aids the growth of cancer tumours. These findings could be [...]

Cardio-oncology services may improve patient care if more widely available

The impact of cancer treatments on cardiovascular health is an important consideration when treating cancer patients, but many hospital training programs have no formal training or services in cardio-oncology and a lack of national guidelines and funding are frequent barriers to establishing such programs, according to a nationwide survey published today in the Journal of [...]