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Tango dancing benefits Parkinson’s patients

Dancing the Argentine tango could have potential benefits for people at certain stages in the development of Parkinson’s disease (PD), according to findings in a new study by researchers at the Montreal Neurological Institute and Hospital -The Neuro, McGill University and the Research Institute of the McGill University Health Centre. The study looked at changes [...]

Epidemic spreading and neurodegenerative progression

Researchers from the Montreal Neurological Institute have used a model inspired by patterns of epidemic disease spreading to map how misfolded proteins propagate within the brain. Proteins which fail to configure correctly (misfolded proteins) are associated with aging and several human neurodegenerative diseases, such as Alzheimer’s. In research published in PLOS Computational Biology, Yasser Iturria [...]

Important piece found in the brain tumour puzzle

Scientists at the Montreal Neurological Institute and Hospital, McGill University and McGill University Health Centre have shown that a member of the protein family known as SUMO (small ubiquitin-like modifier) is a key to why tumour cells multiply uncontrollably, especially in the case of glioblastoma. The SUMO family proteins modify other proteins and the SUMOylation [...]

Discovery of new mechanism underlying translation-dependent synaptic plasticity

The brain is plastic – adapting to the hundreds of experiences in our daily lives by reorganizing pathways and making new connections between nerve cells. This plasticity requires that memories of new information and experiences are formed fast. So fast that the body has a special mechanism, unique to nerve cells, that enables memories to [...]

Mechanism meant to maintain efficiency of brain network involved in neurodegenerative disease

Scientists at the Montreal Neurological Institute and Hospital-The Neuro, McGill University, have made important discoveries about a cellular process that occurs during normal brain development and may play an important role in neurodegenerative diseases. The study’s findings, published in Cell Reports, a leading scientific journal, point to new pathways and targets for novel therapies for [...]