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Study finds childhood stress impacts adult health

A 45-year study of nearly 7,000 people born in a single week in Great Britain in 1958 found psychological distress in childhood — even when conditions improved in adulthood — was associated with higher risk for heart disease and diabetes later in life. The study, published today in the Journal of the American College of [...]

Cohort study explores association between SSRI use and violent crime

Selective serotonin reuptake inhibitor (SSRI) use is modestly associated with violent crime, according to a study published in PLOS Medicine. The cohort study, by Seena Fazel from the University of Oxford, and colleagues, showed in subgroup analysis that this association was evident in participants aged 15-24, but not significant for individuals aged 25 and older. [...]

Most CRT-P patients would not benefit from addition of defibrillator

Most patients with a cardiac resynchronisation therapy (CRT) pacemaker would not benefit from the addition of a defibrillator, according to results from the CeRtiTuDe cohort study presented for the first time today at ESC Congress1 and published in European Heart Journal.2 “The choice between CRT with (CRT-D) or without (CRT-P) a defibrillator remains a contentious [...]

Exercise, however modest, found progressively beneficial to the elderly

Large cohort study finds mortality rate negatively associated with level of physical activity Even exercise of short duration and low intensity has life expectancy benefits for the elderly. Such conclusions have been well examined in the general population, where a recommended exercise program of 30 minutes at least five days a week (or 150 minutes [...]

Longer respiratory support required by ICU patients with poor vitamin D status

Vitamin D status may influence the duration of respiratory support needed for surgical intensive care patients, according to a new cohort study conducted by researchers at Boston’s Massachusetts General Hospital and Harvard Medical School. The study demonstrated that plasma 25-hydroxyvitamin D (25OHD) levels on admission to the surgical ICU were inversely associated with the need [...]