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Researchers mimic viral infection in colon cancer stem cells, identify druggable target to potentially root out disease, end relapse

Researchers targeting colorectal cancer stem cells – the root cause of disease, resistance to treatment and relapse – have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection. The discovery, published online in Cell, illuminates a major shift in understanding anti-tumour mechanisms and identifies [...]

Colorful potatoes may pack powerful cancer prevention punch

Compounds found in purple potatoes may help kill colon cancer stem cells and limit the spread of the cancer, according to a team of researchers. Baked purple-fleshed potatoes suppressed the growth of colon cancer tumors in petri dishes and in mice by targeting the cancer’s stem cells. Colon cancer is the second leading cause of [...]

New strategy improves detection of genetic mutations in hereditary colorectal cancer

Enhanced accuracy and reduced turnaround time of testing can provide vital information for patients suspected of having lynch syndrome and their family members, according to a report in The Journal of Molecular Diagnostics About 3% of colorectal cancers are due to Lynch syndrome, an inherited cancer susceptibility syndrome that predisposes individuals to various cancers. Close [...]

Clinical scoring system suggests possibility of more precise colon cancer screening

A clinical scoring system for colon cancer risk could help physicians identify which average-risk patients could potentially skip a colonoscopy and instead be screened with a less-invasive method. The researchers suggest that this approach could increase the uptake and efficiency of colorectal cancer (CRC) screening. The cross-sectional study is published in Annals of Internal Medicine. [...]

UCLA scientists discover breakthrough experimental therapy to treat colon cancer and chronic inflammatory bowel disease

UCLA scientists have discovered a groundbreaking experimental therapy that has the ability to suppress the development of ulcerative colitis (UC), a disease which causes inflammation in the digestive tract and colon cancer. The treatment utilizes a chemical inhibitor able to block an RNA molecule (microRNA-214) involved in the transmission of genetic information. High levels of [...]