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Discovery of differences between tumours of younger and older colorectal cancer patients may lead to better treatments

Colorectal cancer (CRC) is on the rise among younger patients. Although some of the younger-onset cases can be explained by hereditary factors, the majority arise spontaneously. Researchers have now found that tumours in younger colorectal cancer patients may be molecularly distinct from those of older patients, and that these differences are related to the way [...]

Mayo researchers examine risk factors/patient outcomes associated with colorectal cancer

About 20 percent of colorectal cancer patients have cancers that have spread (metastasized) beyond the colon at the time of their diagnosis. The liver is the most common site for these metastases. The approach to treating primary tumors within the colon and metastatic tumors in the liver continues to evolve; however, it typically involves chemotherapy [...]

Researchers mimic viral infection in colon cancer stem cells, identify druggable target to potentially root out disease, end relapse

Researchers targeting colorectal cancer stem cells – the root cause of disease, resistance to treatment and relapse – have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection. The discovery, published online in Cell, illuminates a major shift in understanding anti-tumour mechanisms and identifies [...]

New strategy improves detection of genetic mutations in hereditary colorectal cancer

Enhanced accuracy and reduced turnaround time of testing can provide vital information for patients suspected of having lynch syndrome and their family members, according to a report in The Journal of Molecular Diagnostics About 3% of colorectal cancers are due to Lynch syndrome, an inherited cancer susceptibility syndrome that predisposes individuals to various cancers. Close [...]

Longer colonoscopies linked to lower cancer rate

If a colonoscopy seems like the type of thing you’d like to get done with quickly, think again. Research by a Veterans Affairs team has confirmed that longer-lasting colonoscopies are associated with lower cancer rates. The findings appeared online July 9, 2015, in Gastroenterology. They were based on nearly 77,000 screening colonoscopies. Experts already know [...]